May 20th = International Clinical Trials’ Day…who knew?

ilindja001p1I’m a nurse…I work in clinical research and I had no idea today was such an important day in this industry. A little bit of reading and I have learned quite a bit.

While the recorded history of clinical research goes all the way back to Biblical times (Book of Daniel); James Lind, MD, is credited as the first physician to have documented a controlled clinical trial of the modern era. While working as a surgeon on a ship, he was appalled by the high mortality of scurvy amongst the sailors. His description of the trial covers all the essential elements of a controlled clinical trial.

Lind describes“”On the 20th of May 1747, I selected twelve patients in the scurvy, on board the Salisbury at sea. Their cases were as similar as I could have them. They all in general had putrid gums, the spots and lassitude, with weakness of the knees. They lay together in one place, being a proper apartment for the sick in the fore-hold; and had one diet common to all, viz. water gruel sweetened with sugar in the morning; fresh mutton-broth often times for dinner; at other times light puddings, boiled biscuit with sugar, etc., and for supper, barley and raisins, rice and currants, sago and wine or the like. Two were ordered each a quart of cyder a day. Two others took twenty-five drops of elixir vitriol three times a day … Two others took two spoonfuls of vinegar three times a day … Two of the worst patients were put on a course of sea-water … Two others had each two oranges and one lemon given them every day … The two remaining patients, took … an electary recommended by a hospital surgeon … The consequence was, that the most sudden and visible good effects were perceived from the use of oranges and lemons; one of those who had taken them, being at the end of six days fit for duty … The other was the best recovered of any in his condition; and … was appointed to attend the rest of the sick. Next to the oranges, I thought the cyder had the best effects …” (Dr James Lind’s “Treatise on Scurvy” published in Edinburgh in 1753)

Fascinating!

Have you ever thought about how new medicines are developed? New medical devices? New treatments?

You guessed it…clinical trials! While this video has a European approval focus…the concept in the USA is the same (in fact often we are working on a trial that has already received approval in Europe but is still in the trial process in the US)…with the final USA approval being with the FDA, the US Food and Drug Administration.

Have you participated in a clinical trial? I’d love to hear your story!

~Jan

Resources:

http://www.acrpnet.org/MainMenuCategory/Membership/International-Clinical-Trials-Day.aspx

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149409/

http://www.fda.gov/default.htm

 

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Happy Birthday, Florence Nightingale!

As a nurse, Florence Nightingale is a very important part of the history of my profession.

Florence Nightingale, the founder of modern nursing was born on May 12, 1820. Her most famous contributions came during the Crimean War; by improving sanitation, hygiene and nutrition, she played a major role in reducing the death rate of wounded soldiers from 50% to 2%. She became known as “The Lady with the Lamp” for making her nightly rounds tending to the wounded.

Here’s an interesting video I found on youtube – “Who was Florence Nightingale?”

And then I found this rare recording of the voice of Florence Nightingale.

I am amazed and astounded by the strength of this woman. Lives saved. History changed. Medicine and nursing forever improved.

Happy Birthday, Florence! Your legacy lives on…your lamp is still shining brightly!

-J

Mother’s Day…

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Mom & I with our buddy Jack!

It’s Mother’s Day afternoon and I’ve enjoyed a beautiful day already: mother/daughter night at the ballet last week, church today, brunch at our favorite after-church-breakfast spot (free box of candy for all Mom’s – too bad I’m not eating sugar…my office will benefit tomorrow!), sweet texts from family & friends near and far, phone call with MIL, a tear-jerking, heart tugging, loving email from my son who is traveling and plans for dinner cooked by hubby, daughter & SIL! My life is full of love indeed.

I’m so very grateful for my mother, who among many other things, raised me to love God; to be kind towards others & treat others as I would want them to treat me; to be a woman of integrity; to serve others; and she instilled in me her love of travel, big cities and sandy beaches! I hope that when I grow up I can be a small measure of the woman my mother is! I love you Mom!!

As this year marks the 100th anniversary of Woodrow Wilson proclaiming Mother’s Day a national celebration in the United States, I thought I’d share some of my favorite Mother’s Day quotes.

  • “Motherhood: All love begins and ends there.” ~Robert Browning
  • “If you have a mom, there is nowhere you are likely to go where a prayer has not already been.” ~Robert Brault
  • “Children are a great comfort in your old age – and they help you reach it faster too.” ~Lionel Kauffman
  • “A man loves his sweetheart the most, his wife the best, but his mother the longest.” ~Irish Proverb
  • “Sing out loud in the car even, or especially, if it embarrasses your children.” ~Marilyn Penland
  • “There is only one pretty child in the world, and every mother has it.” ~Chinese Proverb
  • “A Mom’s hug lasts long after she lets go.” ~Author Unknown
  • “Motherhood has a very humanizing effect. Everything gets reduced to essentials.” ~Meryl Streep
  • “Any mother could perform the jobs of several air-traffic controllers with ease.” ~Lisa Alther
  • “God could not be everywhere, and therefore he made mothers.” ~Rudyard Kipling

I am a mother only because God chose to give me the blessing of raising two beautiful children. I truly believe that is my main purpose in this dance called life. I am learning as I enter this next phase of motherhood…as my children are grown and living out their life’s purpose…that while the role of being their mother changes…the love I have for them only deepens. I can only imagine the love my mother feels for me and my siblings. Wow!

Blessings to all the Mom’s out there! Happy Mother’s Day!

YOLO,

Jan

 

 

First quarter of 2014 is in the books…

How did you do with your first quarter goals? As we begin the 2nd quarter of 2014, it is important to do a review of your accomplishmentsImage (or lack thereof) in the 1st quarter of the year; are you progressing towards your annual goals?

Historically, I set annual goals at the beginning of the year and like a lot of people I often fell short, even forgetting what my original goals were. Both personal and professional. It becomes too easy to just “wing it”…and at the end of the year you/I am often wondering…where did the time go??

Working at Keller Williams, years ago, I learned the value of setting annual goals broken down into monthly goals and further broken down into weekly goals. . This system, called the 4-1-1 (4 weeks, 1 month, 1 year) is one of the best systems I’ve used for keeping my focus on the big picture – my annual goals.

This year, I’ve added in a quarterly review; businesses (and a lot of schools) operate on quarters and this timeframe just makes sense to me. While this is still short term, it is a bigger chunk of time than the monthly review and gives me a slightly bigger picture of where I am on the road to my ultimate destination – my annual goals. I find it also holds me accountable so I don’t lose track of time and procrastinate thinking “I’ve got 9 months left to accomplish that”. The older I get the quicker time seems to fly by; I’m realizing the value of using this goal review period as a management tool of my time. Let me rephrase that…as a management tool of my LIFE!

You’ve heard it before: Plan – Do – Review – Adjust….repeat…

This would be a REVIEW session:

Don’t forget to WRITE IT ALL DOWN!

  1. Review. Look back at the past 3 months. What did you accomplish? Did you progress toward your goals? What did you do to work towards your goals? What worked and what didn’t?
  2. Evaluate. How can you change things to improve progress? Do you need to bring yourself back on track? Are you happy with your progress and just need to stay the course?
  3. Re-prioritize or verify your priorities.  Make your main focus the MAIN focus for the next 3 months. It’s ok to defer appropriate items to later in the year. Just make sure they are part of your next quarterly review.

Going through this process will help you REFOCUS! Remember – just like your mother used to tell you – you can do anything you want and DECIDE to do! It will require action to make it happen. A goal without action is just a plan. You will never reach your goals without action.

This part is especially true for me: Get out of your own way. Take the actions that are necessary so your dreams can come true! Live with the spirit of YOLO!

YOLO!

-Jan

Begin again…

Begin AgainOk, Ok – I realize I have been neglecting my blog. But today…when I opened the blog and realized I haven’t posted yet this entire year…I was shocked! What in the world??

So…it’s time…with the spirit of yolo…to begin again…

 

Life happens…and it’s never too late…to begin again!

Here we go…

YOLO!

-Jan

Tomorrow…

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Tomorrow…the beginning of a brand new year. You can be anyone you want. Accomplish anything you want. I thought I’d share some thoughts from my own reflection, studying, reading, and planning to guide you:

  • The best day of your life is the day you decide your life is your own. No one to lean on, rely on or blame.
  • Life is about the choices you make. Choose wisely.
  • Live your life on purpose.
  • The gift of life is yours, it is an amazing journey, make the best of it.
  • Every single day matters.
  • Love always.
  • Be authentic.
  • Life is now.
  • You are the hero of your own story.
  • Keep your word.
  • Give back.
  • Be grateful.
  • Live passionately.
  • Mentor someone.
  • Forgive.
  • Be present.
  • Don’t “go” through life, GROW through life!

Begin your new book…tomorrow. It just so happens that THIS tomorrow falls as the FIRST day of the NEW YEAR!

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Have a safe and happy celebration wherever you may be.

Make it a good year!! And remember…

YOLO!

~Jan

Oh the places you’ll go…

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You have brains in your head and feet in your shoes

You can steer yourself any direction you choose.

You’re on your own and you know what you know

And you are the one who’ll decide where to go.    ~Dr. Seuss

You guessed it! Goal setting time for the new year….my brains are busy trying to decide where my heart and shoes are steering me. So many options.

YOLO!

Jan

Godspeed, Mr. Mike…

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Our dear friend, Mike McConnell, affectionately “Mr. Mike” to our family, lost his battle with cancer last night. He fought a valiant fight over 4 1/2 years. He and his family handled the diagnosis and ensuing treatments with a grace like I’ve not seen before.

In his last moments he was surrounded by his family whom he loved and adored. He was a believer and we are confident he’s in a better place right now…greeted by those who have passed on before him.

Now we deal with the grief his earthly loss leaves behind. His empty chair.

We love you Mr. Mike and we miss you already. Your spirit will live inside us forever. We will love, pray for, and with, your family to assist them through this transition.

Godspeed.

Surely your goodness and love will follow me all the days of my life,

and I will dwell in the house of the Lord forever.            ~Psalm 23:6

YOLO (never has this been more true),

~Jan

#30DOT Project Complete…New Awareness

 

20131201-124722.jpgOn this first day of December, I am spending time reflecting on the #30DOT (30 Days of Thankful) project I engaged in during the month of November. With the Thanksgiving Holiday in November, a time when we Americans typically spend time expressing gratitude for our blessings, it lends itself to the perfect time for a thanks”giving” project.

My Facebook feed had several people engaging in a similar project and more than a handful of naysayers. Without giving attention to the negativity I continued on my path. It is said it takes at least 21 days to create a habit. I can’t imagine anything bad coming from a habit of thankfulness and gratitude. Some days I chose to post my thanksgivings to Facebook and Twitter and other days they were private.

What I DID notice…was a definite increased awareness of the goodness and beauty in my life. I found myself, with this increased awareness, thinking positive thoughts much more frequently. And when the “turkey’s” in my life threatened to pull me down…and yes…I have some in my life, I simply found a moment of awareness and realization that even the negative serves to confirm that I am ALIVE! And then…BAM!! I was hit with thanks”giving” and gratitude once again.

I am thankful I challenged myself with this project. I am thankful I grew during this project. If you’ve never done a similar project I challenge you to try it. Living a life of gratitude and thanksgiving forces me to focus on the positive and that can only be a good thing.

YOLO! -Jan